AI & ML jobs in South San Francisco
26 live roles · 5 companies · 17 with stated pay
Hiring now
26 AI and machine learning roles in South San Francisco are open right now across 5 companies. Genentech alone accounts for 21 of them, so this list leans heavily on one employer. 10 were posted in the last 30 days.
More roles here state pay than the 35% that do site-wide.
Every posting here is mid-level or above, and 85% are senior or lead.
Market snapshot
- Hiring
- Genentech (21)·Calico (2)·Blue Matter·structuretx·Zipline
- Roles
- AI Research (16)·Machine Learning Engineering (6)·AI Engineering (3)·ML Platform & Ops
- Levels
-
- Director1
- Senior21
- Mid4
- Remote
- 0 of 26
- Stated pay
- 17 of 26 · $167,400–$343,900
- Posted
- 10 in the last 30 days
- Verified
- Oct 22, 2026
this job's paywhere most pay sits here, $167,400–$343,900scale $100,000–$490,000
Senior Machine Learning Engineer, Agentic Science/Generative Models, AI for Biology & Translation (AIBT) Genentech · South San Francisco · Machine Learning Engineering $168,100–$312,300 today Machine Learning Engineer (AI Enablement) Genentech · South San Francisco · Machine Learning Engineering $147,600–$274,000 2d ago Machine Learning Engineer/Senior Machine Learning Engineer - Devops, AI for Drug Discovery Genentech · New York · Machine Learning Engineering In listing 3d ago Senior AI Engineer- Imaging Genentech · South San Francisco · AI Engineering $168,100–$312,300 3d ago Principal Scientist, SOP & Workflow Automation Champion, AI for Drug Discovery (AIDD) Genentech · South San Francisco · AI Research $201,300–$373,800 5d ago Senior Physical AI & Robotics Scientist - Lab Automation Genentech · South San Francisco · AI Research $168,100–$312,300 9d ago AI Scientist/Senior, Clinical & Molecular Genomics Modeling, BRAID Genentech · South San Francisco · AI Research In listing 2w ago Senior Machine Learning Scientist, AI for Biology & Translation (AIBT) Genentech · South San Francisco · AI Research In listing 2w ago Director, AI Engineering structuretx · South San Francisco · AI Engineering $248,000–$310,000 3w ago Machine Learning Engineer/Senior Machine Learning Engineer, Agentic Systems, AI for Drug Discovery Genentech · South San Francisco · Machine Learning Engineering In listing 3w ago ML Infrastructure Engineer Zipline · South San Francisco · ML Platform & Ops $160,000–$250,000 6w ago Principal Machine Learning Engineer, Foundation Models, AI for Drug Discovery Genentech · New York · Machine Learning Engineering $192,500–$357,500 6w ago AI Engineer / Senior AI Engineer Blue Matter · South San Francisco · AI Engineering $120,000–$170,000 7w ago Senior Principal DSX Data Scientist, AI Genentech · South San Francisco · AI Research $207,480–$385,320 7w ago Principal Data Scientist - RDT Applied AI Genentech · South San Francisco · AI Research $185,200–$343,900 8w ago Principal Machine Learning Scientist, Frontier Research, AI for Drug Discovery (AIDD) Genentech · South San Francisco · AI Research In listing 8w ago Senior Machine Learning Scientist, Protein ML, AI for Drug Discovery (AIDD) Genentech · South San Francisco · AI Research $167,400–$310,800 2mo ago Machine Learning Engineer, Infra, AI for Drug Discovery Genentech · South San Francisco · Machine Learning Engineering In listing 2mo ago Senior Scientist, Antibody Developability/Biophysics & Portfolio Support, AI for Drug Discovery (AIDD) Genentech · South San Francisco · AI Research $168,100–$312,300 2mo ago Principal Scientist, Portfolio & gRED Interface-Biologics, AI for Drug Discovery (AIDD) Genentech · South San Francisco · AI Research $201,300–$373,800 2mo ago Senior / Principal Machine Learning Scientist, Scientific Reasoning Models, AI for Drug Discovery Genentech · New York · AI Research In listing 2mo ago Senior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT) Genentech · South San Francisco · AI Research $147,800–$274,400 3mo ago Senior/Principal Machine Learning Scientist, Perturbation Biology, AI Biology & Translation (AIBT) Genentech · South San Francisco · AI Research In listing 4mo ago Senior / Staff Machine Learning Research Engineer Calico · South San Francisco · AI Research $220,000–$290,000 5mo ago Machine Learning Scientist / Senior Machine Learning Scientist Calico · South San Francisco · AI Research $170,000–$240,000 5mo ago Machine Learning Scientist, Scientific Reasoning Models, AI for Drug Discovery Genentech · New York · AI Research In listing 8mo ago 5 companies hiring in South San Francisco
- Genentech21 roles
- Calico2 roles
- Blue Matter1 role
- structuretx1 role
- Zipline1 role