Scientist, Safety
Neurocrine Open · verified Oct 22, 2026 At a glance
Mid-level AI Research role at Neurocrine. US CA San Diego · full-time · $89,800–$123,000 base.
aimlroles summary, based on the employer's posting.
What you'll do
- Help identify and assess safety signals, then carry out product risk plans during development and after approval
- Review safety data and contribute safety content to regulatory reports, clinical protocols, study reports and product labeling
- Prepare periodic and one-off safety submissions, and help answer questions from health authorities
- Review scientific literature and gather safety responses for internal teams and external partners
- Support safety surveillance procedures, audits, inspections and clinical-trial pharmacovigilance work
What you bring
- A related scientific bachelor’s degree or RN qualification plus at least two years in pharmacovigilance, clinical research or medical research
- Alternatively, a related scientific master’s degree with relevant industry experience, or a PharmD or PA qualification with some experience
- Knowledge of pharmacovigilance rules and practices, signal assessment, risk planning and aggregate safety reports
- Working familiarity with drug safety systems such as ARISg or Argus
Who this fits
This role suits someone with a scientific background who can assess safety data and work across multidisciplinary teams. The position is based in San Diego, California.
From the employer
Who We Are:
Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. (*in collaboration with AbbVie)
About the Role:
Supports safety surveillance and risk management activities for assigned Neurocrine products through the lifecycle of the product. Supports the production of aggregate reports, signal management and safety review meetings, providing safety support for investigational products including new drug applications and other regulatory filings, managing responses to health authorities and maintaining relationships with PV business partners. May also work with the DSPV Operations group to support case processing activities as needed by the department._
Your Contributions (include, but are not limited to):
Participate in the process of safety signal management to detect, analyze, and investigate safety signals
Executes risk management plans for assigned Neurocrine products during all phases of development and post approval
Perform assigned safety data review and may interpret information to support safety evaluations
Support preparation of safety input (e.g., author and review) for drug-safety related regulatory reports and clinical study documents (including clinical study protocols, Informed Consent Forms, Investigator Brochures, Integrated Summary of Safety (ISS), MedDRA coding of AEs, product labeling, Company Core Data Sheet (CCDS))
Assist preparation of safety related regulatory submission documents including periodic and ad-hoc aggregate reports (eg, DSUR, IND Annual Report, PADER, PBRER, PSUR, etc.) and safety-related health authority requests in accordance with regulatory requirements
Participate in multidisciplinary teams at Neurocrine involving R & D project teams, clinical project managers, business management, regulatory, and others to execute clinical trials, assess new product opportunities, develop clinical research strategy and product development plans
Participate in testing processes and conventions for safety surveillance activities including maintenance of SOPs and guidelines
Collects responses to safety questions from internal and external stakeholders including business partners
Perform review of scientific literature for safety information
Support clinical trial PV activities including providing safety content review of clinical protocols, study reports, Investigators Brochure, informed consents and other related documents, as applicable
Assist with document requests and preparing responses during inspections and audits as well as management of any corrective and preventative actions
Other duties as assigned
Requirements:
BS/BA degree in related scientific field or RN degree AND 2+ years of pharmacovigilance or clinical and/or medical research or equivalent experience OR
MS/MA degree in related scientific field AND some relevant industry experience preferred OR
PharmD or PA AND some experience preferred
Recognizes fundamental anomalies in data points and identifies issues in experiments / processes
Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals
Strong knowledge of one scientific discipline
Good knowledge of scientific principles, methods and techniques
Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools
Ability to work as part of a team
Strong computer skills
Good communications, problem-solving, analytical thinking skills
Detail oriented
Team player with ability to function in a multi-disciplinary environment
Self-motivated, detail oriented, and able to prioritize and plan effectively
Knowledge of ICH guidelines, US and EU pharmacovigilance regulatory requirements
Working knowledge of drug safety systems (e.g. ARISg and Argus)
Knowledge of current pharmacovigilance practices
Shows ability to evaluate, interpret and synthesize scientific data
Knowledge of signal evaluation and risk management
Working knowledge of aggregate data analysis, interpretation and synthesis
Ability to review periodic aggregate safety reports (e.g. PBRERs, DSURs) and RMPs
Good knowledge of current pharmacovigilance practices
Neurocrine Biosciences is an EEO/Disability/Vets employer.
We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.
_
The annual base salary we reasonably expect to pay is $89,800.00-$123,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.